Tanto o treinamento intervalado de alta intensidade quanto o treinamento contínuo de intensidade moderada diminuem os níveis de fetuína-A em ratos machos alimentados com uma dieta rica em gordura.
DOI:
https://doi.org/10.47197/retos.v56.104318Palavras-chave:
interval training, continuous training, obesity, insulin resistance, healthy lifestyleResumo
Antecedentes: A fetuína-A é uma hepatocina que está aumentada na obesidade, e uma dieta rica em gordura (DH) contribui para essa condição. A obesidade é caracterizada pelo aumento do índice de massa corporal (IMC) e está diretamente relacionada à resistência à insulina. Este estudo tem como objetivo analisar a diferença entre a eficácia do treinamento intervalado de alta intensidade (HIIT) e do treinamento contínuo de intensidade moderada (MICT) nos níveis de fetuína-A, insulina, glicemia de jejum (FBG).) e IMC em alimentados com HFD. ratos. Métodos: Vinte e quatro ratos Wistar machos foram divididos em quatro grupos: DC (dieta padrão), DH (somente DH), DH-IT (DH e HIIT) e DH-CT (DH e MICT). A DH consistia em uma dieta padrão com 2 ml adicionais/200 gramas de peso corporal de óleo de gordura de porco por dia. No grupo HFD-IT, a natação com carga de 9% do peso corporal, com períodos de descanso intermitentes e curtos, foi utilizada como exercício, enquanto o grupo HFD-CT recebeu carga de 6% do peso corporal e natação contínua. A natação ocorreu cinco dias por semana durante quatro semanas. Os níveis de fetuína-A e insulina foram medidos pelo método de ensaio imunoenzimático (ELISA), e os níveis de FBG foram medidos com um glicosímetro. Resultados: Os níveis de fetuína-A foram significativamente mais baixos nos grupos HFD-IT e HFD-CT em comparação com o grupo HFD (p<0,05). O grupo HFD-CT apresentou diminuição significativa nos níveis de GJ (p<0,05), mas não o grupo HFD-IT. Não houve diferenças no IMC e nos níveis de insulina entre os grupos após quatro semanas de tratamento (p>0,05). Conclusões: HIIT e MICT têm eficácia semelhante na redução dos níveis de fetuína-A. Além disso, o MICT também conseguiu reduzir os níveis de FBG.
Palavras-chave: treinamento intervalado, treinamento contínuo, dieta hiperlipídica, fetuína-A, insulina, estilo de vida saudável.
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