O exercício físico como chave para ativar a queima de gordura através da ativação da proteína desacopladora 1 (ucp1) no tecido adiposo: uma revisão de âmbito
DOI:
https://doi.org/10.47197/retos.v66.114284Palavras-chave:
Exercício físico, aptidão física, bastão, ucp1, ácido gordoResumo
Fundamento: Para além de ser um importante elemento relacionado com a termogénese, o exercício é uma excelente intervenção para reduzir a obesidade. Pesquisas recentes indicam que as “exerquinas”, ou substâncias químicas libertadas durante a atividade física, podem alterar a ativação do tecido adiposo castanho (TAM) e o escurecimento do tecido adiposo branco. No entanto, os processos compostos pelos quais a ativação do TAM é afetada por variáveis periféricas causadas pelo exercício não são bem compreendidos. Além disso, o impacto da atividade física na ativação do TAM não é bem compreendido. Uma importante proteína responsável pela termogénese adaptativa que ocorre durante o escurecimento do tecido adiposo branco e castanho é a proteína desacopladora 1 (UCP1). Objectivo: Este estudo tem como objectivo analisar o efeito do exercício físico no aumento da proteína desacopladora 1 (UCP1) em ratinhos.
Materiais e métodos: Pesquisamos diversas bases de dados bibliográficas para a nossa pesquisa de revisão sistemática, incluindo a Pubmed, a Web of Science e a Science Direct. Artigos que abordassem a atividade física e a UCP1 publicados nos últimos cinco anos. As bases de dados Web of Science, Pubmed e Science Direct foram utilizadas para localizar 380 artigos publicados. Para esta revisão sistemática foram selecionados e revistos dez artigos que cumpriam os critérios de inclusão. Este estudo utilizou o Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) para avaliar os procedimentos operacionais padrão.
Resultados: Os resultados deste estudo indicam que o exercício físico demonstrou aumentar a expressão de UCP1.
Conclusões: Está demonstrado que a atividade física aumenta a expressão da UCP1. O processo de aumento do metabolismo e da termogénese será desencadeado por este aumento, fazendo com que o gasto energético gerado pelo tecido adiposo aumente.
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