PLS-SEM analysis of factors influencing quality of life in Indonesian patients with chronic illness

Authors

  • Rahmi Inayati Universitas Malikussaleh
  • Hizir Sofyan Universitas Malikussaleh, Indonesia
  • Teuku Tahlil Universitas Malikussaleh, Indonesia
  • Marthoenis Marthoenis Universitas Malikussaleh, Indonesia

DOI:

https://doi.org/10.47197/retos.v74.117015

Keywords:

Illness acceptanc, quality of life, non-communicable diseases, medication adherence, physical activity

Abstract

Introduction: Chronic illnesses often led to declines in both physical and psychological health, making their management a complex public health concern. These conditions disrupted daily functioning and reduced overall well-being.

Objective: The study aimed to examine the relationship between illness acceptance, physical activity, medication adherence, and quality of life among individuals diagnosed with hypertension, diabetes mellitus, and chronic obstructive pulmonary disease in Pidie regency, Aceh, Indonesia.

Methodology: A cross-sectional design was applied to a sample of 379 adults aged thirty-five to seventy years who had been diagnosed with one of the three chronic conditions. Data were obtained using structured questionnaires that measured physical activity, medication adherence, illness acceptance, and quality of life. Statistical analyses included Pearson correlation and multiple regression to determine the strength and direction of relationships among variables.

Results: Physical activity emerged as the strongest predictor of quality of life, followed by medication adherence, both showing statistically significant associations. Illness acceptance demonstrated a weak positive relationship with quality of life, and demographic characteristics did not show meaningful influence on quality of life outcomes.

Discussion: The findings aligned with previous research indicating that active engagement in physical movement and consistent treatment behaviours were central contributors to improved well-being in chronic illness populations, while psychological acceptance alone had limited independent impact.

Conclusions: The study highlighted the need for nursing interventions that reinforce regular physical activity and consistent medication use while integrating psychosocial strategies to support illness acceptance and enhance overall quality of life.

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Published

04-12-2025

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Original Research Article

How to Cite

Inayati, R., Sofyan, H., Tahlil, T., & Marthoenis, M. (2025). PLS-SEM analysis of factors influencing quality of life in Indonesian patients with chronic illness. Retos, 74, 707-717. https://doi.org/10.47197/retos.v74.117015